Department for Biotechnical Problems of Diagnostic
About us
                          Laboratory of marker compounds

Scientific direction: investigation of the phenomenon of super-fast freezing of biological objects of varying degrees of complexity with the development of formulations and freezing protocols for each level of biological structures.
       Projects implemented by the Laboratory:

Investigation of the phenomenon of ultrafast cooling of biological objects for creation of a device for cryopreservation "(Implementation term: 2013-2016)
1. Perepelytsina O., Ugnivenko A., Burlaka D., Bezugly S., Sydorenko M. Optimization of Human Somatic Cell Cryopreservation Protocols by Polyethylene Glycols // Medical and Clinical Chemistry. - 2016. - t. 18, № 3. - S. 5-12.
2. Patent for utility model "The method of cryopreservation of somatic cells" No. 117693, u201612432, published 07.10.2017.
3. The patent for the utility model "The medium for cryopreservation of somatic cells" No. 117694, u201612433, published on 07/10/2017.
"The phenomenon of ultrafast cooling of biological objects: the development of effective freezing protocols". (Deadline 2017-2021)

"Investigation of the influence of metal-containing and carbon nanomaterials as a divergent matrix in vitro cultivation of cells" of the target comprehensive program of fundamental research "Fundamental Problems of Nanostructured Systems, Nanomaterials, Nanotechnologies" of the National Academy of Sciences of Ukraine. (2010-2014).


1. Yakymchuk O.M., Perepelytsina O.M., Rud A.D., Kirian I.M., Sydorenko M.V. Impact of carbon nanomaterials on the formation of multicellular spheroids by tumor cells // Physical status solid. - 2014 - P. 1-7 / DOI 10.1002 / psssa.201431358.
2. Yakymchuk O.M., Perepelytsina O.M., Rud A.D., Kirian I.M., Belyy N.M., Sydorenko M.V. Ultrafine dispersed nanodiamonds: effect on molecular processes in the cell // Proceedings of the E-MRS 2014 Spring Meeting? May 26-30, 2014, Lille, France.
3. Perepelytsina O.M., Sydorenko M.V., Demianenko D.P., Rud A.D., Kirian I.M. Influence of carbon nanomaterials in 3D culture of tumor cells // Collection of scientific works - International scientific and practical conference: Nanotechnologies and nanomaterials, Lviv, Ukraine, 17-30.08.2014.
4. Yakymchuk OM, Perepelitsina OM, Sidorenko MV, Demyanenko D.P., Rud AD, Kiriyan I.M., Bilyi M.N. Ultrasonic Diamonds: Impact on Molecular Processes in Tumor Cells // Collected Works - International Scientific and Practical Conference: Nanotechnologies and Nanomaterials, August 17-30, 2014, Lviv, Ukraine.
5. Perepelytsina O.M., A.D. Rud, Gergeliuk T.S., Biliy M. M., Sydorenko M.V., Kiryan I.M. Biochemical and cytotoxic properties of ultra dispersed diamonds // Compilation of scientific articles "Carbon Particles in Condensed Matter", VII International Conference "Fullerenes and Nanostructures in Condensed Matter", Minsk, Belarus, June 9-12, 2013 - p. 334-339 .
6. E.M. Perepelytsina, M.V. Sidorenko, D.P. Demianenko, A.D. Rud, N.M. Beliy The study of the influence of ultrafine nanodiamonds on tumor cell population in vitro // International scientific and practical conference: Nanotechnologies and nanomaterials, 29.08-1.09.2013, Bukovel, Ukraine
7. Е.М. Perepelitsina, AD Rud, E.M. Yakymchuk, IM Kiryan, N.M. White, MV Sidorenko Investigation of the Possibility of Using Nanomaterials as Extracellular Matrix // IV International Scientific Conference "Nanoscale Systems: Structure, Properties, Technologies" - 2013.

Web-design Perepelitsyna Anastasia
Investigation of pro- and anti-oncogenic activity of biological substances of cellular origin
Investigation of the influence of factors of cellular origin on the population of stem cell tumors in the culture of tumor microspheroids
Testing of carbon-protein construct for the target delivery of antitumor drugs
Development of a cell-based test system for assessing the effectiveness and mechanisms of exposure to antitumor drugs
Determination of biosecurity and cytotoxic influence of gold nanoparticles on monolayer and spheroidal culture of tumor cells
Creation of hardware and software complex for spectral investigation of thin films of biological substances in the average IR range